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 運動科學 學術論文與專利發明發表

August 2011 to July 2021


專利與發明  Patents and Inventions

  心血管疾病Cardiovascular disorders  

  1. High-intensity interval training recuperates capacity of endogenous thrombin generation in heart failure patients with reduced ejection fraction. Thromb Res. 2020; 87:159-165.

  2. High-intensity interval training is associated with improved long-term survival in heart failure patients. J Clin Med. 2019; 8: E409.

  3. High-intensity interval training enhances mitochondrial bioenergetics of platelets in patients with heart failure. Int J Cardiol. 2019;274:214-220.

  4. Cerebral desaturation in heart failure: Potential prognostic value and physiologic basis. PLoS One. 2018;13:E0196299.

  5. Effect of exercise training on exercise capacity and quality of life in patients with heart failure. Int J Cardiol. 2018 Jun 15;261:144-145.

  6. Short-term intensive training attenuates the exercise-induced interaction of mono-1/2 cells and platelets after coronary bypass in cardiac patients. Thromb Haemost. 2017 Aug 30;117(9):1761-1771.

  7. Detection of exercise periodic breathing using thermal flowmeter in patients with heart failure. Med Biol Eng Comput. 2017;551189-1198.

  8. Passive leg raising correlates with future exercise capacity after coronary revascularization. PLoS One. 2016;11:e0157205.

  9. Aerobic interval training elicits different hemodynamic adaptations between heart failure patients with preserved and reduced ejection fraction. Am J Phys Med Rehabil. 2016;95:15-27.

  10. Central and peripheral hemodynamic adaptations during cardiopulmonary exercise test in heart failure patients with exercise periodic breathing. Int Heart J. 2015;56:432-438.

  11. Cardiac rehabilitation in patients with heart failure. Acta Cardiol Sin. 2014;30:353-359.

  12. Effect of multidisciplinary disease management for hospitalized heart failure under a national health insurance programme. J Cardiovasc Med (Hagerstown). 2015;16:616-624.

  13. Modified high-intensity interval training increases peak cardiac power output in patients with heart failure. Eur J Appl Physiol. 2014;114:1853-1862.

  14. Anemic comorbidity reduces capacity of endogenous thrombin generation and is associated with consumptive coagulopathy in patients with heart failure. Int J Cardiol. 2013;168:4965-4967.

  15. Effect of aerobic interval training on erythrocyte rheological and hemodynamic functions in heart failure patients with anemia. Int J Cardiol. 2013;168:1243-1250.

  16. Anemia, heart failure and exercise training. Int J Cardiol. 2013;168:1525-1526.

  17. Exertional periodic breathing potentiates erythrocyte rheological dysfunction by elevating pro-inflammatory status in patients with anemic heart failure. Int J Cardiol. 2013;167:1289-1297.

  18. Aerobic interval training improves oxygen uptake efficiency by enhancing cerebral and muscular hemodynamics in patients with heart failure. Int J Cardiol. 2013;167:41-50.

  19. Non-invasive cardiac index monitoring during cardiopulmonary functional testing provides additional prognostic value in patients after acute heart failure. Int Heart J. 2012;53:364-369.

  20. Edema index-guided disease management improves 6-month outcomes of patients with acute heart failure. Int Heart J. 2012;53:11-17.

  21. Suppression of cerebral hemodynamics is associated with reduced functional capacity in patients with heart failure. Am J Physiol Heart Circ Physiol. 2011;300:H1545-555.


   中風與周邊血管疾病 Stroke and peripheral vascular disorders   

  1. Cycling exercise training enhances platelet mitochondrial bioenergetics in patients with peripheral arterial disease: a randomized controlled trial. Thromb Haemost. 202l;121:900-912.

  2. Application of stepper in cardiopulmonary exercise test for patients with hemiplegia. Medicine (Baltimore). 2020;99:e21058.

  3. Increased serum brain-derived neurotrophic factor with high-intensity interval training in stroke patients: A randomized controlled trial. Ann Phys Rehabil Med. 2020:101385.

  4. Exercise training enhances platelet mitochondrial bioenergetics in stroke patients: a randomized controlled trial. J Clin Med. 2019;8:2186.

  5. A preliminary investigation of the association of sleep with inflammation and oxidative stress biomarkers and functional outcomes after stroke rehabilitation. Sci Rep. 2017;7:8634.

  6. Effects of neuromuscular electrical stimulation on arterial hemodynamic properties and body composition in paretic upper extremities of patients with subacute stroke. Biomed J. 2014;37:205-210.


  延緩老化與預防失能 Delay senescence and prevent disability  

  1. Circulating MicroRNA-486 and MicroRNA-146a serve as potential biomarkers of sarcopenia in the older adults. BMC Geriatr. 2021;21:86.

  2. Weight control in older adults with knee osteoarthritis: a qualitative study. BMC Musculoskelet Disord. 2020;21:e504.

  3. Adherence to home-based rehabilitation in older adults with diabetes after hip fracture. Nurs Res. 2019;68:383-389.

  4. Effects of a diabetes-specific care model for hip fractured older patients with diabetes: A randomized controlled trial. Exp Gerontol. 2019;126:110689

  5. Diabetic neuropathies influence recovery from hip-fracture surgery in older persons with diabetes. Exp Gerontol. 2019;119:168-173.

  6. The effectiveness of a virtual reality-based Tai Chi exercise on cognitive and physical function in older adults with cognitive impairment. Dement Geriatr Cogn Disord. 2018;46:358-370.

  7. The effects of self-management intervention among middle-age adults with knee osteoarthritis. J Adv Nurs. 2016;72:1825-1837.


  改善免疫、降低感染與預防癌症 Improve immunity, reduce infection and prevent cancer  

  1. Effects of normoxic and hypoxic exercise training on the bactericidal capacity and subsequent apoptosis of neutrophils in sedentary men. Eur J Appl Physiol. 2018;118:1985-1995.

  2. Effects of normoxic and hypoxic exercise regimens on lymphocyte apoptosis induced by oxidative stress in sedentary males. Eur J Appl Physiol. 2017;117:2445-2455.

  3. Exercise training alleviates hypoxia-induced mitochondrial dysfunction in the lymphocytes of sedentary males. Sci Rep. 2016;6:35170.

  4. Presurgical symptom profiles predict quality of life 2 years after surgery in women with breast cancer. Support Care Cancer. 2016;24:243-251.

  5. Adherence to prescribed exercise time and intensity declines as the exercise program proceeds: findings from women under treatment for breast cancer. Support Care Cancer. 2015;23:2061-2071.

  6. Effects of normoxic and hypoxic exercise regimens on monocyte-mediated thrombin generation in sedentary men. Clin Sci (Lond). 2015;129:363-374.

  7. Interval and continuous exercise regimens suppress neutrophil-derived microparticle formation and neutrophil-promoted thrombin generation under hypoxic stress. Clin Sci (Lond). 2015;128:425-436.

  8. Activation of lymphocyte autophagy/apoptosis reflects haemodynamic inefficiency and functional aerobic impairment in patients with heart failure. Clin Sci (Lond). 2014;127:589-602.

  9. Weight change trajectory in women with breast cancer receiving chemotherapy and the effect of different regimens. J Clin Nurs. 2014;23:2757-2768.

  10. Effects of interval and continuous exercise training on CD4 lymphocyte apoptotic and autophagic responses to hypoxic stress in sedentary men. PLoS One. 2013;8:e80248.

  11. Hypoxic exercise training promotes antitumour cytotoxicity of natural killer cells in young men. Clin Sci (Lond). 2011;121:343-353.

  12. Hypoxic exercise training reduces senescent T-lymphocyte subsets in blood. Brain Behav Immun. 2011;25:270-278.


  體能與健康促進科技化 Physical fitness and health promote technology  

  1. Eccentric cycling training improves erythrocyte antioxidant and oxygen releasing capacity associated with enhanced anaerobic glycolysis and intracellular acidosis. Antioxidants (Basel). 2021;10:285.

  2. A randomized controlled trial of enhancing hypoxia-mediated right cardiac mechanics and reducing afterload after high intensity interval training in sedentary men. Sci Rep. 2021;11:12564.

  3. High-intensity interval training improves left ventricular contractile function. Med Sci Sports Exerc. 2019;51:1420-1428.

  4. High-intensity interval training improves erythrocyte osmotic deformability. Med Sci Sports Exerc. 2019;51:1404-1412.

  5. Adherence to home-based rehabilitation in older adults with diabetes after hip fracture. Nurs Res. 2019;68:383-389.

  6. High-intensity interval training improves mitochondrial function and suppresses thrombin generation in platelets undergoing hypoxic stress. Sci Rep. 2017;7:4191.

  7. High-intensity Interval training enhances mobilization/functionality of endothelial progenitor cells and depressed shedding of vascular endothelial cells undergoing hypoxia. Eur J Appl Physiol. 2016;116:2375-2388.

  8. Cycling exercise training alleviates hypoxia-impaired erythrocyte rheology. Med Sci Sports Exerc. 2016;48:57-65.

  9. The effects of a biosensing game on the physical health-related fitness of chronic schizophrenic patients. Hu Li Za Zhi. 2016;63:49-58.

  10. Absolute hypoxic exercise training enhances in vitro thrombin generation by increasing procoagulant platelet-derived microparticles under high shear stress in sedentary men. Clin Sci (Lond). 2013;124:639-649.

  11. Hypoxic exercise training causes erythrocyte senescence and rheological dysfunction by depressed Gardos channel activity. J Appl Physiol. 2011;111:382-391.

Cardiovascular disorders  
Stroke and peripheral vascular disorders
Improve immunity, reduce infection and prevent cancer
Delay senescence and prevent disability
Physical fitness and health promote technology






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